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THE REGULATION OF THE ACTIVITY OF CYTOTOXIC T CELL LYMPHOCYTES WITH MHC CLASS I PEPTIDES
THE REGULATION OF THE ACTIVITY OF CYTOTOXIC T CELL LYMPHOCYTES WITH MHC CLASS I PEPTIDES
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机译:MHC I类肽对细胞毒性T细胞淋巴细胞活性的调节
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摘要
Fragments from the polymorphic domains of Class I HLA antigen domains are used to modulate T-cell activity. The peptides are from the alpha 1- or alpha 2 domains, particularly of the HLA-A, and B antigens. The peptides may be conjugated to other compounds to be used in diagnosis and therapy. The peptides may block lysis, CTL proliferation or have other regulating effects.
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