BENZAMIDINE DERIVATIVES SUBSTITUTED BY CYCLICAL AMINOSATES OR HYDROXYLIC ACIDS AND THEIR USE AS ANTICO-AGULANTS

摘要

This invention is directed to benzamidine derivatives substituted by cyclic amino acid and cyclic hydroxy acid derivatives which are useful as anti-coagulants. This invention is also directed to pharmaceutical compositions containing the compounds of the invention, and methods of using the compounds to treat disease-states characterized by thrombotic activity.