BIS(ALKNYL)CARBINOLS, METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOLS, OPTICALLY ACTIVE TERTIARY ALCOHOLS, AND OPTICALLY ACTIVE AMINOALCOHOLS

摘要

PPROBLEM TO BE SOLVED: To provide an optically active tertiary alcohol capable of being turned into a useful chiral building block, by a simple procedure. PSOLUTION: This optically active alkenylalkynylcarbinol is given by acting LiAlHSB4/SBand a catalytic amount of an optically active aminoalcohol on a bis(alkynyl)carbinol having two equivalent alkynyl groups in toluene at a room temperature, so as to selectively reduce one of the alkynyl groups. PCOPYRIGHT: (C)2005,JPO&NCIPI