C. their use in the development of Kosen insecticides and genes required for reproduction or survival and / elegans

摘要

The present invention relates to several C. elegans genes and gene products identified by means of RNA-mediated interference (RNAi) as required for the viability, growth or reproduction of nematodes and to functional orthologues of said genes and gene products found in other nematode species, including all biologically-active derivatives thereof. The invention also comprises the use of said genes and gene products in the development of anti-nematode or other pesticidal agents and in methods for diagnosis and treatment of diseases associated with the infection or presence of nematodes.