BILE ACID-ADSORBING POLYMER AND CHOLESTEROL LOWERING AGENT

摘要

PROBLEM TO BE SOLVED: To provide a bile acid-adsorbing polymer capable of more selectively adsorbing only bile acid and to provide a cholesterol lowering agent capable of solving the dose problem which is a burden for a patient in a cholesterol lowering agent comprising a conventional anion exchange resin and having excellent compliance.;SOLUTION: The bile acid-adsorbing polymer is a crosslinking polymer having bile acid-adsorbing performance and the bile acid adsorption amount (A) in a physiological salt aqueous solution of 6.4 mM bile acid concentration and 9.9 mM aliphatic acid concentration and ion-exchange capacity (B) satisfy the relation of formula (1): A/B×100≥40 (1).;COPYRIGHT: (C)2004,JPO