PROBLEM TO BE SOLVED: To provide octahydroindeno[5, 6-d][1, 3]dioxole-2-thione derivative which is a production intermediate of ottelione A and B exhibiting a potent tubulin polymerization inhibitory activity and expected to be used as an anti-tumor agent, and a method for producing the same.;SOLUTION: This octahydroindeno[5, 6-d][1, 3]dioxole-2-thione derivative is expressed by general formula (1) (wherein, R1, R2 are the same or different and are each H or a protecting group of hydroxy group) and an ottelione analog are provided.;COPYRIGHT: (C)2004,JPO&NCIPI
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