Production method of adipic acid dimethyl 5-cyano-valeric acid, or adipic acid,

摘要

'(Is alkyl C1~C12 H or, where R) compound of' formula (1) _{NC-CH 2 -CH} 2 _-CH 2 _-CH 2 -CO 2 R or (2) adipic acid, A process for the preparation of (3) dimethyl adipate, ligand, respectively, using 3-pentenenitrile, or (2) 3-pentenoic acid 3-pentenoic acid methyl, it is selected as the Group VIII metal as a substrate In the presence of an acid promoter and a method of contacting a nucleophilic agent and carbon monoxide substrate is disclosed. Group VIII metal, a phosphine ligand and palladium were selected in the presence of an acid promoter, preferably, each water (a) or alcohol, or (b) water, the nucleophile (c) methanol is.