Exon intron junction determining device and the gene region determining apparatus and method for determining the them

摘要

The present invention provides a device and a method for efficiently determining an exon-intron junction with high accuracy. The device of the invention is useful for determining an exon-intron junction in a gene region of the genome. This device comprises an input part in which data on a cDNA of organism 1 and the corresponding gene region of organism 2 are input; an operation part in which two non-overlapped sequences i and j, each having at least 10 bases, are extracted from the gene region of organism 2, and, with respect to sequences i and j extracted, s(i, j) defined by s(i, j) = s(x, yij) - Cä(b1 - j) + (i - a2) - (B1 - A2)ü2 is calculated; a junction determination part in which a combination of sequences i and j that maximizes s(i, j) is selected; and an output part in which the position of the exon-intron junction determined is output. IMAGE