Humanized chimeric monoclonal antibody recognizing epidermal growth factor receptor (EGF-R) and diagnostic and therapeutic uses thereof

摘要

New humanized and chimeric monoclonal antibodies that recognize EGF-R and comprise an artificial sequence at least of the FRs of the heavy chain variable region of a human immunoglobulin. The hypervariable regions of both monoclonal antibodies is the following amino acid sequence: IMAGE Use of the antibodies for therapeutical and diagnostic purposes.