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The hetero-or aryl-substituted polycyclic aryl useful for selective inhibition of the coagulation cascade 4-pyrones
The hetero-or aryl-substituted polycyclic aryl useful for selective inhibition of the coagulation cascade 4-pyrones
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机译:杂芳基或芳基取代的多环芳基可用于选择性抑制凝血级联4-吡喃酮
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摘要
The invention relates to polycyclic aryl and heteroaryl substituted 4-pyrone compounds useful as inhibitors of serine proteases of the coagulation cascade and compounds, compositions and methods for anticoagulant therapy for the treatment and prevention of a variety of thrombotic conditions including coronary artery and cerebrovascular diseases.
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