Using the gradient for characterizing molecular interactions and devices to form a temperature gradient

摘要

Novel apparatus for generating a temperature gradient (100) is described. The device comprises (114a, 114b) electrical connector attached to one side of the wafer, preferably a semiconductor wafer and (110). Method of moving the temperature gradient in the layer is described. It is possible by using a temperature gradient on the layer, molecules, analyzes of biological macromolecules, especially. The present invention also includes an improved method to confirm the thermal stability of the binding complex.