gurukagon reseputa

摘要

(57) [Abstract] The present invention provides an isolated DNA molecule comprising a DNA segment encoding a glucagon-receptor. In addition, DNA constructs comprising those are combined in operable condition to additional DNA segments required for expression of the first DNA segment and a first DNA segment encoding a glucagon receptor, and thus It also provides host cells containing the DNA construct. Also provided is a method of detecting the presence of glucagon antagonists, the presence of (a) glucagon agents, the present invention is, for a time and conditions sufficient to permit binding of the compound to the receptor, the compounds , the recombinant glucagon receptor is bound to associated response through its path and response pathway, bleached; against the stimulus of the response pathway and (b) due to the glucagon agent alone, that to the glucagon receptor It also provides a method of detecting the presence of glucagon material therefrom, and detecting a decrease in the stimulus of the response pathway resulting from the binding of a compound, comprising the step.