Tyrosine phosphorylation cut groove-related protein (PSTPIP)

摘要

(57) [summary] The present invention relates to PSTPIP novel polypeptides that are bound by the PEST family of protein tyrosine phosphatase, is dephosphorylated by it. Specifically, its homologue in other mammals and native murine PSTPIP polypeptide as well as the invention relates to a functional derivative thereof. The present invention relates to a recombinant host cell transformed using a vector capable of nucleic acids encoding these proteins, that contain the nucleic acid, and expressing it, and the nucleic acid. There is also provided an assay for identifying antagonists and agonists of the PSTPIP polypeptide of the present invention methods, and for inducing the polymerization of actin monomers in a eukaryotic cell.