A vasectomy procedure is performed using a vas irrigation solution having a spermicidal agent that (a) acts to reduce the viability of downstream sperm following a vasectomy procedure and (b) has been established as safe and non-toxic in humans when administered by intravenous or other routes of injection for the treatment of other conditions. Preferred spermicidal agents are methylene blue and diltiazem. A kit having a pair of single-use, pre-filled injection devices is also disclosed.
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