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Method of treating strongyloides infections and medicaments therefor

机译：治疗类圆线虫感染的方法及其药物

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摘要

Infections caused by parasitic nematodes of the genera Strongyloides, Ancyclostoma, Necator, Haemonchus, Ascaris, or Trichuris in humans and other mammals are treated by administration to an infected individual of an amount of a C₈-C₁₆-alpha,beta-unsaturated aliphatic aldehyde. Such compounds are useful for killing nematode worms of the genera listed above. A particularly useful compound of this class, effective against S. stercoralis infections, is E-2-dodecenal, having structural formula (1). chemistry chemdraw filechemistry mol file

机译：对人和其他哺乳动物中由类线虫，无环线虫，Necator，Haemonchus，Ascaris 或 Trichuris 属的寄生线虫引起的感染在人类和其他哺乳动物中进行治疗C _{8 -C _{16 -α，β-不饱和脂族醛的合成此类化合物可用于杀死上述属的线虫。这类特别有用的化合物，对I硫有效。甾体感染是E-2-十二烯，具有结构式（1）。 <图像文件=“ US20040214900A1-20041028-C00001.GIF” he =“ 36.48645” id =“ EMI-C00001” imgContent =“ undefined” imgFormat =“ GIF” wi =“ 196.83405“ /> 化学chemdraw文件化学mol文件}} 展开▼

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公开/公告号US2004214900A1

专利类型

公开/公告日2004-10-28

原文格式PDF

申请/专利权人 FORBES WAYNE M.;ROBINSON RALPH D.;REESE PAUL B.;
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申请/专利号US20030424091

发明设计人 WAYNE M. FORBES;RALPH D. ROBINSON;PAUL B. REESE;
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申请日2003-04-28

分类号A61K31/11;

国家 US

入库时间 2022-08-21 23:21:08

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机译：治疗类圆线虫感染的方法及其药物

4. composition, pharmaceutical composition, effervescent dosage form, multiple unit oral oral pharmaceutical composition, extended release pharmaceutical dosage form, enteric coated pharmaceutical dosage form, stable pharmaceutical dosage form for oral administration to mammalian subjects, method for treating diseases acid-related diseases by inhibiting gastric acid secretion, method for treating a bacterial infection caused or caused by helicobacter pylori, process for preparing a compound of formula 3, process for preparing a compound of formula 5, use of a compound of formula 1 for the preparation of a medicament for treating gastric acid-related diseases by inhibiting gastric acid secretion, use of a compound of formula 1 for the preparation of a medicament for treating a bacterial infection caused or caused by helicobacter pyl or use of a compound of formula 1 for the preparation of a medicament for treating gastric acid-related diseases by inhibiting gastric acid secretion [P] . BRPI0617987A2 . 2011-08-16

机译：组合物，药物组合物，泡腾剂型，多单位口服口服药物组合物，缓释药物剂型，肠溶衣药物剂型，向哺乳动物受试者口服给药的稳定药物剂型，通过抑制胃酸治疗疾病的方法酸分泌，治疗由幽门螺杆菌引起或引起的细菌感染的方法，制备式3化合物的方法，制备式5化合物的方法，式1化合物在制备用于治疗胃的药物中的用途通过抑制胃酸分泌来治疗与酸有关的疾病，将式1的化合物用于制备用于治疗由幽门螺杆菌引起或引起的细菌感染的药物，或将式1的化合物用于制备用于治疗的药物通过抑制胃酸分泌来治疗胃酸相关疾病

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