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Sericin-containing material, process for producing the same method of using the same

机译:含丝胶的材料,其制备方法,使用相同的方法

摘要

The object of the present invention is to elucidate a biologically active function of a component constituting undegraded sericin and to provide a novel medical material, cosmetic material, etc. utilizing the functional composition. Disclosed is a cell growth promoter obtainable by elution from a fiber discharged by a domestic silkworm, e.g., cocoon filaments or the like, wherein the cell growth promoter comprises sericin having a molecular weight of about 400,000 as measured by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) as a main component. This cell growth promoting agent (substance) is extremely useful because growth of cells is promoted when it is used in a wound dressing material, a vascular endothelium forming material and an organ forming material for medical use, in a cell culture base material for biological use, or in a cosmetic material for skin care use.
机译:本发明的目的是阐明构成未降解的丝胶蛋白的组分的生物活性功能,并利用该功能组合物提供新颖的医用材料,化妆品材料等。公开了一种可通过从家蚕排出的纤维如茧丝等中洗脱而获得的细胞生长促进剂,其中所述细胞生长促进剂包含通过十二烷基硫酸钠-聚丙烯酰胺凝胶电泳测得的分子量约为400,000的丝胶。 (SDS-PAGE)作为主要成分。这种细胞生长促进剂(物质)非常有用,因为当用于生物用途的细胞培养基质材料中的伤口包扎材料,血管内皮形成材料和医学用途的器官形成材料中时,细胞的生长被促进。 ,或用于皮肤护理的化妆品中。

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