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Ion exchanger for lipoproteins separation and lipoproteins separation method using the same

机译:用于脂蛋白分离的离子交换剂和使用该离子交换剂的脂蛋白分离方法

摘要

An ion exchanger for lipoproteins separation, which is an ion exchanger obtained by introducing an ion exchange group into surface hydrophilic-treated porous organic polymer particles (D) prepared by subjecting the surface of porous organic polymer particles (A) to hydrophilic treatment, wherein said hydrophilic treatment is carried out by allowing the porous organic polymer particles (A) to undergo addition reaction with a compound (B) having a cyclic other group or/and a hydrophilic group and a polymerizable unsaturated double bond and then to undergo copolymerization with a polymerizable vinyl monomer (C) having a cyclic ether group or/and a hydrophilic group, and wherein the ion exchange capacity is 0.15 milliequivalent or less per 1 g of dry ion exchanger, introduced amount of the compound (B) is from 0.1 to 45% by weight based on the porous organic polymer particles (A), and copolymerized amount of the compound (C) is from 5 to 60% by weight based on the addition product obtained by allowing the porous organic polymer particles (A) to undergo addition reaction with the compound (B).
机译:用于脂蛋白分离的离子交换剂,其是通过将离子交换基团引入通过对多孔有机聚合物颗粒(A)的表面进行亲水处理而制备的表面亲水处理的多孔有机聚合物颗粒(D)中获得的离子交换剂,其中所述通过使多孔有机聚合物颗粒(A)与具有环状其他基团和/或亲水基团和可聚合的不饱和双键的化合物(B)进行加成反应,然后与可聚合的可聚合基团进行共聚,来进行亲水化处理。具有环状醚基或/和亲水基的乙烯基单体(C),相对于每1g干式离子交换剂,离子交换容量为0.15毫当量以下,化合物(B)的导入量为0.1〜45%相对于多孔有机聚合物颗粒(A),以重量计,化合物(C)的共聚量为5至60重量%,基于所获得的加成产物。通过使多孔有机聚合物颗粒(A)与化合物(B)进行加成反应。

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