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C12 modified erythromycin macrolides and ketolides having antibacterial activity

机译:具有抗菌活性的C12修饰的红霉素大环内酯类和酮醇类

摘要

Antimicrobial macrolide compounds are provided having formulas II: embedded image;as well as pharmaceutically acceptable salts, esters or prodrugs thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infections by the administration of such compounds; and processes for the preparation of the compounds.
机译:提供了具有式II的抗微生物大环内酯化合物:<化学ID =“ CHEM-US-00001”> <图像alt =“嵌入式图像” file =“ US06756359-20040629-C00001.GIF” he =“ 132.5079” imgContent =“ undefined” imgFormat =“ GIF” wi =“ 186.9966” /> ;及其药学上可接受的盐,酯或前药;包含此类化合物的药物组合物;通过施用此类化合物治疗细菌感染的方法;以及化合物的制备方法。

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