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Immunogenicity using a combination of dna and vaccinia virus vector vaccines
Immunogenicity using a combination of dna and vaccinia virus vector vaccines
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机译:结合使用dna和牛痘病毒载体疫苗的免疫原性
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摘要
This invention relates to improved methods of inducing an immune response for the prevention or treatment of HIV-1 infection by using a nucleic acid vaccine in conjunction with a recombinant viral vaccine, e.g., a poxvirus vaccine, to potentiate and broaden the immune response. The present invention further provides a particularly effective vaccine regimen comprising a DNA vaccine used in combination with a poxvirus virus, especially NYVAC or ALVAC.
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