首页>
外国专利>
Method and composition for increasing CD4+ T lymphocyte immune responsiveness
Method and composition for increasing CD4+ T lymphocyte immune responsiveness
展开▼
机译:增加CD4 + T淋巴细胞免疫反应性的方法和组合物
展开▼
页面导航
摘要
著录项
相似文献
摘要
A method and composition to restore and/or increase immune responsiveness in CD4+ T lymphocytes that display a loss of immune function (i.e., immune unresponsiveness) after CD4 is ligated by human immunodeficiency virus (HIV) gp120 are disclosed. Such a method and composition are useful for restoring immune surveillance and host defense capabilities to an HIV-infected patient, for causing HIV-infected T lymphocytes to become targets of the immune system, and for increasing the survival and development of CD4+ T lymphocytes in HIV-infected patients so the immune system can be reconstituted. Also disclosed are a method to identify putative regulatory compounds useful in a composition of the invention and a method to identify suitable candidate patients for treatment by a method of the invention.
展开▼