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Chiral salen catalyst and methods for the preparation of chiral compounds from racemic epoxides by using new catalyst

机译:手性Salen催化剂及使用新催化剂由外消旋环氧化物制备手性化合物的方法

摘要

The present invention relates to new chiral salen catalysts and methods for the preparation of chiral compounds from racemic epoxides by using new catalyst. More particularly, the present invention is to provide novel chiral salen catalysts and their uses for producing chiral compounds having high optical purity to be used as raw materials for preparing chiral medicines or food additives in a large scale economically, wherein the chirl salen catalyst having a particular molecules structure can be reused continuously without any activating process of used catalysts and cause no or little racemization after the reaction is completed because it maintains its catalytic activity after the reaction process.
机译:本发明涉及新的手性塞伦催化剂和通过使用新的催化剂由外消旋环氧化物制备手性化合物的方法。更特别地,本发明提供了新颖的手性塞林催化剂及其在制备具有高光学纯度的手性化合物中的用途,所述手性塞林催化剂被用作经济地大规模制备手性药物或食品添加剂的原料,其中所述手性塞林催化剂具有特定的分子结构可以连续重复使用,而无需使用过的催化剂进行任何活化过程,并且在反应完成后不会或几乎不会发生外消旋化,因为它在反应过程后保持了催化活性。

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