Method and fabrication of the potentiometric chemical sensor and biosensor based on an uninsulated solid material

摘要

In this invention, a potentiometric electrochemical sensor and biosensor based on an uninsulated solid-state material was presented. ;This potentiometric electrochemical sensor and biosensor is different from the traditional ion sensitive field effect transistor (ISFET), which the sensing electrode was separated from the field effect transistor and was only connected to the field effect transistor by a metal line. Therefore the sensing electrode can be seen as a low cost disposable electrode. The sensing structure of this sensor is more rigid than the glass electrode, and the fabricative cost is lower than those of glass electrode and traditional ISFET electrode. In addition, this device shows a linear pH sensitivity of approximately 5860 mV/pH with the high correlation coefficient up to 0.999 in a concentration range between pH2 and pH12. Therefore this device owns a high and linear sensitivity. In addition, this device will not be affected by light interference. ;Based on the above characteristics, a disposal-sensing device can be achieved. Thus, this invention has a high feasibility in the electrochemical sensor and biosensor.