embedded image;in which A and B are nitrogen or carbon, provided only one of A and B is nitrogen; and R1-R6 are as defined in the specification, wherein R2 with R5 may form a ring, and/or two R4 groups may form a six-membered aryl or heteroaryl ring, optionally having a substituent R6 forming a ring with R3."/> Cannabinoid receptor modulators, their processes of preparation, and use of cannabinoid receptor modulators for treating respiratory and non-respiratory diseases
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Cannabinoid receptor modulators, their processes of preparation, and use of cannabinoid receptor modulators for treating respiratory and non-respiratory diseases

机译:大麻素受体调节剂,其制备方法以及大麻素受体调节剂在治疗呼吸道和非呼吸道疾病中的用途

摘要

Use of a compound for treating a respiratory disease in a mammal wherein the compound is a cannabinoid receptor modulator is disclosed. Compounds useful as cannabinoid receptor modulators for treating respiratory and non-respiratory leukocyte-activation associated diseases comprise compounds of formula (I), embedded image;in which A and B are nitrogen or carbon, provided only one of A and B is nitrogen; and R1-R6 are as defined in the specification, wherein R2 with R5 may form a ring, and/or two R4 groups may form a six-membered aryl or heteroaryl ring, optionally having a substituent R6 forming a ring with R3.
机译:公开了化合物在治疗哺乳动物的呼吸系统疾病中的用途,其中该化合物是大麻素受体调节剂。用作大麻素受体调节剂以治疗呼吸道和非呼吸道白细胞激活相关疾病的化合物包括式(I)的化合物,<化学编号=“ CHEM-US-00001”> <图像alt =“嵌入式图像” file =“ US06653304 -20031125-C00001.GIF“ he =” 73.45485“ imgContent =” undefined“ imgFormat =” GIF“ wi =” 151.4457“ /> ;其中A和B为氮或碳,前提是A和B中只有一个是氮;和R 1 -R 6 如规范中所定义,其中R 2 与R 5 可以形成一个环和/或两个R 4 基团可形成六元芳基或杂芳基环,视情况具有取代基R 6 形成与R 3 < / Sub>。

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