Polymorphic forms of a generic azabiciclo 2,2,2 octan-3-yl - 3 - Amine, their pharmaceutical compositions, Treatment procedure and Process for its production.

摘要

A single Crystalline polymorphic form of citrate (2S, 3S) - N - (methoxy 5 t butilfenilmetil - 2 - Diphenylmethyl - 1-azabicyclo [2,2,2] octan-3-yl - 3 - Amine (CITRATE MONOHYDRATE) and a Pharmaceutical composition. The pharmaceutical Composition of the polymorphic form of CITRATE MONOHYDRATE has the Stability needed for a Formulation for treating emesis.The Administration of this Pharmaceutical composition is an oral immediate release dosage form, preferably in the form of a tablet or capsule, or intravenously. It also describes the preparation of the polymorphic form.