N - oxides saturated Heterocycles containing nitrogen and are replaced with quinoloncarboxilicos and Process for its production.

摘要

N-nitrogenous saturated heterocyclic oxide, replaced by quintorboxyl acid with formula (1),Among them, it represents the structural debris (2),(3)(4) And (5);R4 represents a linear or separable C1-4 tar, which can be optionally replaced by hydroxy or methyl ether, cycloacrylonitrile, c1-3; R5 represents hydrogen, methyl, phenyl, sulfur or pyridine; R6 represents hydrogen or C1-4 tar; R7 represents hydrogen or C1-4; R8 represents hydrogen or C1-4 tar; R2 represents hydrogen or asphalt. C1-4, optionally substituted by thyroid and benzene, 2-oxopropilo, benzoic acid and ethoxymethyl ester; a = n, = ch -,=C (halogen) - o = C (OCH3) -,And hydrate, acid additive or salt with drug use and production process