Homogeneous hydrochloride Crystalline polymorphs of N - (3-ethynylphenyl) - 6, 7 - bis - (2-methoxyethoxy) 4 quinazolinamina; Pharmaceutical compositions made with these polymorphs; use thereof in the preparation of these compositions, Process for the preparation of the Polymorph B

摘要

The polymorphous salt of 1. N - (3-ethylphenyl) - 6, 7-Bis (2-methoxyformate) - 4-kundienylhydrazide is described and claimed to have stable polymorphous, characterized by being designated as' polymorphous B, characterized by an X-ray powder diffraction pattern of 2-titanium, expressed at a rate of about 6.26, 12.48, 13.39, 16.96, 20; 20. 21.10, 22.98, 24.46, 25.14 and 26.91. In addition, in the development of drugs for the treatment of extremely widespread diseases such as cancer and other items mentioned in the title, these applications are described and requirements are put forward.