Process for the manufacture of acid - 2 (IL - 2 - Co.) - 3 - (2 - and piridincarboxu00edlicos Co. - 2 - il) - 3 - quinolincarboxu00edlicos formula (1), wherein R and R1 are either h, c1-4 alkyl or Halogen, alcoxialquil, or R and R1 are in whole (CH = CH - ch = CH) which consists of the reaction; A Diester of acids, 2 - or 3 - piridindicarboxu00edlicos 2.3 - quinolindicarboxu00edlicos formula (2),Where R and R are defined as in formula (1) and R2 is a c1-4 alkyl, 2 - amino - 2.3 - dimetilbutiramida (ADBA) and a metal hydride in an Inert Solvent, Dissolving in water, the salts of the acids - 2 (IL - 2 - Co.) - 3 - piridincarboxu00edlicos and - 2 (Il - 2 - Co.) - 3 - quinolincarboxu00edlicos Acidifying Solutions, and isolating the products of formula (1).The diesters and piridindicarboxu00edlicos acid 2,3 - 2.3 - quinolindicarboxu00edlicos REACT with 2 - amino - 2.3 - dimetilbutiramida in presence of alkali metal hydrides in an Inert Solvent, at a temperature range between 0 and 50 with subsequent conversion to metal salts S (1) free acids.
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