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Noninvasive transdermal vaccine

机译:无创透皮疫苗

摘要

Non invasive skin antigen vaccine, preventive or therapeutic vaccine related to superdeformed vehicles. The vaccine includes: (a) a dialysis device, which is a penetrant, suspended or dispersed in an aqueous solution, in the form of a drop of fluid, surrounded by a film like coating, at least two different substances, or two different substance forms, and tends to increase. Solubility there is at least one factor 10 different from the solubility of the preferred water medium of these substances or their forms,Therefore, the average diameter of a substance consisting of two or more soluble substances or a homogenous substance with an average diameter is smaller than its average diameter.O-polymerize the most insoluble substance or substance form and / or the most soluble component, which often dissolves through the drop, and the content of the component is up to 99 moles of the concentration required to dissolve the drop, orIt is the place where the elastic deformation energy of 99 moles of Undissolved Water Drop saturated concentration (maximum) and / or membrane water drop is at least 5 times lower, It is preferable to be at least 10 times lower than red blood cells or diphenyl phosphate with a mobile crystalline chain, or ideally more than 10 times lower, (b) a compound that releases, specifically induces or carries out cell or hydrogen activities on its own, And (c) antigens or alejano. This report also deals with immunization methods in mammals,To obtain a protective or therapeutic immune response.
机译:非侵入性皮肤抗原疫苗,与超变形载体有关的预防或治疗疫苗。该疫苗包括:(a)透析装置,该透析装置是渗透剂,以液滴形式悬浮或分散在水溶液中,并被薄膜状包衣,至少两种不同物质或两种不同物质包围形式,并趋于增加。溶解度与这些物质或它们的形式的优选水介质的溶解度有至少一个不同的系数10,因此,由两种或更多种可溶性物质组成的物质的平均直径或平均直径小于O型聚合最难溶的物质或物质形式和/或最易溶的成分,通常通过液滴溶解,并且该成分的含量高达溶解液滴所需浓度的99摩尔,或者是99摩尔未溶解水滴的饱和浓度(最大值)和/或膜水滴的弹性变形能至少低5倍的地方,最好比红血球或磷酸二苯酯低至少10倍(b)一种在其上释放,特异性诱导或进行细胞或氢活性的化合物(c)抗原或alejano。该报告还涉及哺乳动物的免疫方法,以获得保护性或治疗性免疫应答。

著录项

  • 公开/公告号AR037312A1

    专利类型

  • 公开/公告日2004-11-03

    原文格式PDF

  • 申请/专利权人 IDEA AG;

    申请/专利号AR2000P100372

  • 发明设计人 CHOPRA AMLA;CEVC GREGOR;

    申请日2000-01-27

  • 分类号A61K9/127;A61K38/19;A61K39/39;A61K39/35;A61K39/02;A61K39/12;A61P37/00;

  • 国家 AR

  • 入库时间 2022-08-21 23:12:24

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