Method for treating severe chronic bronchitis (bronchiectase) with an aerosol antibiotic

摘要

"METHOD FOR TREATMENT OF CHRONIC SEVERA BRONCHITIS (BRONCHIECTASE) WITH AN ANOSBIO IN THE FORM OF AEROSOL". A method for the treatment of severe chronic bronchitis (bronchiectasis) using a concentrated aminoglycoside antibiotic formulation that releases the antibiotic into the pulmonary endobronchial space, including alveoli, in an aerosol or dry powder that has a mass average diameter predominantly between 1 and 5. microns. The method comprises administering the antibiotic at a concentration one to ten thousand times greater than the minimum inhibitory concentration of the target organism. Preferably, the method comprises the endobronchial administration of aerosol or dry tobramycin powder to treat pseudomonas infections in patients with severe chronic bronchitis (bronchiectasis).