Cysteine protease inhibitors with structure of 2 - cyano - 4 - amino pyrimidine and cathepsin K Inhibitory activity for the treatment of inflammations and other diseases

摘要

The Invention provides compounds of formula I, or a Salt or Ester of the pharmaceutically acceptable (i) wherein the symbols have the meanings as defined, which are inhibitors of cathepsin K and are used for the treatment of diseases and Pharmaceutical Co Medical ndiciones in which is involved the cathepsin K, for exampleVarious conditions including inflammation, rheumatoid arthritis, Osteoarthritis, osteoporosis and Tumors