Procedure for forecasting the development of breast cancer and compounds used in its prevention and treatment

摘要

This invention concerns in vitro method for prognosticating the progress of breast cancer, comprising detecting or quantifying the level of 17beta-hydroxysteroid dehydrogenase (17HSD) type 1 enzyme in breast tumor tissue sample, wherein the presence of said 17HSD type 1 enzyme is indicative of severe progress of breast cancer. Furthermore, the invention also concerns the use of a 17HSD type 1 enzyme inhibitor for prevention or treatment of breast cancer. This invention concerns also the use of compound A in the manufacture of a pharmaceutically acceptable preparation useful as 17HSD inhibitor.