METHOD OF PRODUCING ACTIVE IMMUNITY WITH VACCINE CONJUGATE, A VACCINE PREPARATION USEFUL FOR THE PRODUCTION OF SAID VACCINE CONJUGATE AND A PROCESS FOR THE MANUFACTURE OF SAID VACCINE

摘要

A method of producing active immunity against a bacterial or protozoal disease in a subject comprises administering to the subject a vaccine conjugate comprising a live bacteria or protozoa and a neutralizing factor bound to the live bacteria or protozoa. The neutralizing factor is selected from the group consisting of antibodies and antibody fragments. The live bacteria or protozoa is one capable of producing disease in the subject, and the antibody or antibody fragment is one capable of neutralizing the live bacteria or protozoa.