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alpha-AMINO ACID PHENYL ESTER DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM
alpha-AMINO ACID PHENYL ESTER DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM
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机译:α-氨基酸苯酯衍生物和包含它们的药物组合物
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摘要
The present invention relates to alpha-amino acid phenyl ester derivatives having general formula (I) wherein R1 is (C1-3)alkyloxy; R2 is (C1-3)alkyl, (C1-3)alkyloxy or (C2-3)alkenyl; R3 is hydrogen, (C1-3)alkyl, (C1-3)alkyloxy or (C2-3)alkenyl; R4 is (C1-6)alkyl; R5 and R6 are independently (C1-6)alkyl, (C2-6)alkenyl, (C2-6)alkynyl or aralkyl, each of which may be optionally substituted with (C1-3)alkyloxy, (C1-3)alkyloxycarbonyl, cyano or NR7R8; R7 and R8 are independently (C1-6)alkyl; or a pharmaceutically acceptable salt thereof. The invention also relates to pharmaceutical compositions comprising said derivatives, and to the use of these alpha-amino acid phenyl ester derivatives as hypnotics for the induction and maintenance of general anaesthesia.
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