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COMPOSITIONS AND METHODS FOR DETECTING PRE-CANCEROUS CONDITIONS IN CELL AND TISSUE SAMPLES USING 5, 10, 15, 20-TETRAKIS (CARBOXYPHENYL) PORPHINE.
COMPOSITIONS AND METHODS FOR DETECTING PRE-CANCEROUS CONDITIONS IN CELL AND TISSUE SAMPLES USING 5, 10, 15, 20-TETRAKIS (CARBOXYPHENYL) PORPHINE.
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机译:使用5、10、15、20-四(羧基)甲酚在细胞和组织样品中检测癌前状况的组合物和方法。
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摘要
Presented is a method to detect precancerous states in mammalian cell and tissue samples comprising incubating a sample wit solubilized 5, 10, 15, 20-tetrakis (carboxyphenyl) porphine (TCPP), measuring TCPP fluorescence in the sample, and categorizing the sample, and categorizing the sample as non-cancerous, precancerous or cancerous based on TCPP fluorescence, as correlated with the respective states of the cells. In conjunction with the method a detection, a novel and more efficient method of solubilizing TCPP is presented, as well as a composition comprising TCPP solubilized by this method.
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