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Use of prostane - derivatives as well as their combination with antibiotics for the treatment of bacterial meningitis
Use of prostane - derivatives as well as their combination with antibiotics for the treatment of bacterial meningitis
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机译:前列腺素衍生物及其与抗生素结合用于治疗细菌性脑膜炎的应用。
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PCT No. PCT/EP96/03481 Sec. 371 Date Apr. 23, 1998 Sec. 102(e) Date Apr. 23, 1998 PCT Filed Aug. 6, 1996 PCT Pub. No. WO97/06806 PCT Pub. Date Feb. 27, 1997A method is described for treating bacterially induced meningitis, comprising administering a prostane derivative of formula I or Ia wherein X1, X2, X3, X4, X5, R1, R2, R3 and R4 are as described below, and the -O-R3- group is in the alpha - or beta -configuration. The prostane derivative can optionally comprise or serve as an adjuvant, and it can be administered in combination with an antiobiotic.
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