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HETEROCYCLIC COMPOUNDS OF BENZENOSULFONAMIDE AS BRADIQUININ ANTAGONISTS
HETEROCYCLIC COMPOUNDS OF BENZENOSULFONAMIDE AS BRADIQUININ ANTAGONISTS
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机译:苄索磺酰胺的杂多环化合物作为杂环素的拮抗剂
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摘要
The invention concerns compounds selected among the group consisting of (i) compounds of formula (I) wherein: Het1 represents a nitrogenous heterocycle with 5 apices, in particular imidazole, pyrazole, or triazole; Het2 represents a nitrogenous heterocycle with 4, 5 or 6 apices, selected among the heterocycles: (II) wherein R1 and R2 are defined as mentioned in the description; and (ii) their additive salts. The invention also concerns the method for preparing said compounds and their use in therapy, in particular for treating pathologies involving bradykinine.
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