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PREPARATION OF PHARMACEUTICAL STABILITY OF NASAL ORAL OR SUB-LINGUAL APPLICATION CONTAINING DESMOPRESSIN
PREPARATION OF PHARMACEUTICAL STABILITY OF NASAL ORAL OR SUB-LINGUAL APPLICATION CONTAINING DESMOPRESSIN
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机译:含有去氨加压素的鼻内或舌下应用的药物稳定性的制备
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摘要
A stable, nasally, orally or sublingually applicable pharmaceutical preparation for administering to patients has an aqueous solution of desmopressin as the active agent. Said solution contains an osmoticum and a buffer which maintains the pH-value in the range of 4 to 6, preferably about 5. The buffer is malic acid, preferably in the form of a racemate. Thereby an improved stability of the desmopressin content in the preparation is obtained.
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