DRUG FOR PREVENTING VASCULAR RESTENOSIS AND INSTRUMENT TO BE EMBEDDED IN VESSEL COATED WITH THE DRUG

摘要

ABSTRACT A drug for preventing vascular restenosis comprises a compound that inactivates [err]1-protease inhibitor and [err]2macroglobulin as active constituents, which are associated with occurrence of vascular restenosis after coronary artery intervention. Preferably, the drug is coated on a surface of an implantableintravascular device and locally administered to the affected area by application of the implantable intravascular device to a narrowed area.