USE OF MACROLID COMPOUNDS FOR THE TREATMENT OF ACUTE PULMONARY INJURIES.

摘要

Use of the tricyclic compounds of the following formula (I): ** formula ** in which each of the adjacent pairs R1 and R2, R3 and R4, and R5 and R6 independently (a) are two adjacent hydrogen atoms, but R2 may also be an alkyl group, or (b) they may form another bond formed between the carbon atoms to which they are attached; R7 is a hydrogen atom, a hydroxy group, a protected hydroxy group or an alkoxy group, or an oxo group together with R1; R8 and R9 are independently a hydrogen atom or a hydroxy group; R 10 is a hydrogen atom, an alkyl group, an alkyl group substituted with one or more hydroxy groups, an alkenyl group, an alkenyl group substituted with one or more hydroxy groups, or an alkyl group substituted with an oxo group.