USE OF 19-NOR-VITAMIN D COMPOUNDS FOR THE PREVENTION OF HYPERPHOSPHATEMIA IN KIDNEY DISORDER PATIENTS

摘要

The 19-nor-vitamin D analogs, and particularly 19-nor-1.alpha.,25-dihydroxyvitamin D2, possess low calcemic and phosphatemic activitywhile also having the ability to suppress parathyroid hormone (PTH)production. The suppressive effect on PTH secretion of these 19-nor analogs without significant changes in serum calcium or serum phosphorusmake them ideal tools for the treatment of secondaryhyperparathyroidism in patients having kidney disorders.