USE OF 19-NOR-VITAMIN D COMPOUNDS FOR THE PREVENTION OF HYPERPHOSPHATEMIA IN KIDNEY DISORDER PATIENTS

摘要

The 19-nor-vitamin D analogs, and particularly 19-nor-1 alpha ,25-dihydroxyvitamin D2, possess low calcemic and phosphatemic activity while also having the ability to suppress parathyroid hormone (PTH) production. The suppressive effect on PTH secretion of these 19-nor analogs without significant changes in serum calcium or serum phosphorus make them ideal tools for the treatment of secondary hyperparathyroidism in patients having kidney disorders.