AN IMPROVED PROCESS FOR THE PREPARATION OF NEFAZODONE HYDROCHLORIDE

摘要

A process for the preparation of Nefazodone hydrochloride comprising directconversion of semicarbazide dihydrochloride 3 into Nefazodone hydrochloridewhich process involves a reaction of triethyl orthopropionate in the presenceoftrimethylsilylchloride and hydrochloric acid.