SIM2 POLYPEPTIDES AND POLYNUCLEOTIDES AND USES OF EACH IN DIAGNOSIS AND TREATMENT OF OVARIAN, BREAST AND LUNG CANCERS

摘要

A method of diagnosing predisposition to, or presence of ovarian cancer,breast cancer and/or lung cancer in a subject is provided. The methodcomprises determining a level of SIM2 in a lung tissue, breast tissue and/orovarian tissue of the subject, the level being correlatable withpredisposition to, or presence or absence of the ovarian cancer, breast cancerand/or lung cancer, thereby diagnosing predisposition to, or presence ofovarian cancer, breast cancer and/or lung cancer in the subject.