PROTEIN TYROSINE PHOSPHATASE-PRL-1 A A MARKER AND THERAPEUTIC TARGET FOR PANCREATIC CANCER

摘要

Using gene expression profiling, the present Invention identifies Proteintyrosine phosphatase IVA member 1 (PRL-1) as a diagnostic marker andtherapeutic target for pancreatic cancer. The Invention therefore providesmethods for prediction and detection of PRL-1 associated cancers, andevaluation of inhibitors of PRL-1. The Invention also provides a method oftreating or preventing pancreatic cancer in a subject.