RESEARCH MODELS FOR THE EVALUATION OF RETINOPATHY OR MICROANGIOPATHY AND USES THEREOF

摘要

An organism that may be utilized for research in fields such as diabetic retinopathy and microangiopathy lacks a functional version of the gene coding for the PDGF-B protein and exhibits reduced pericyte formation. One way to create such a research organism is to delete exon 4 of the PDGF-B gene.