Mta1s, a steroid hormone receptor corepressor

摘要

The present invention concerns the use of methods and compositions to diagnose, treat and identify therapeutic molecules for cancer, in particular hormone insensitive cancers. The invention includes polypeptides and nucleic acids encoding polypeptides of MTA1s, a novel protein derived from alternative splicing of the MTA1 gene. Other embodiments include antibody compositions for the diagnosis and prognosis related to the aberrant expression of the MTA1s polypeptide.