Method for determining the presence of an unconventional transmissible agent responsible for transmissible subacute spongiform encephalopathy

摘要

The present invention relates to a method of identification of genes, the level of expression of cell is correlated to the presence of an agent which can be transmitted is not a conventional (d), or of a pathological of the prion protein (prp). It also carries, on a method of determining the presence of a d which is responsible for a transmissible spongiform encephalopathy subchronic in a biological sample, as well as on a process for the selection of a compound capable of slowing, stopping or prevent the development of a 20%. Finally, are also included in the present invention, the primers, the nucleotide probes and the kits for implementing the method of determining the presence of a d. / p