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METHODS FOR INHIBITING ALLERGIC INFLAMMATION AND OTHER RESPONSES INITIATED BY POLLENS, MOLDS, AND OTHER NON-ANIMAL DERIVED ALLERGENS

机译:抑制由花粉,霉菌和其他非动物源性过敏原引起的过敏性发炎和其他反应的方法

摘要

Disclosed are methods for treating or preventing allergic inflammation in a subject and methods for treating or preventing one or more symptoms of allergic inflammation in a subject. The methods include administering to the subject a compound which inhibits reactive oxygen species. Also disclosed are methods for reducing a non-animal-derived allergen’s ability to initiate an allergenic process and for reducing prooxidant activity of a non-animal-derived allergen. The methods include contacting the non-animal-derived allergen with an agent which inhibits reactive oxygen species. Methods for screening a compound for its usefulness as an agent for reducing a non-animal-derived allergen’s ability to initiate an allergenic process and/or for its usefulness as a therapeutic agent for treating or preventing allergic inflammation and /or the symptoms associated therewith are also disclosed.
机译:公开了在受试者中治疗或预防变应性炎症的方法以及在受试者中治疗或预防变应性炎症的一种或多种症状的方法。所述方法包括向受试者施用抑制活性氧种类的化合物。还公开了降低非动物源性变应原启动变应原过程的能力以及降低非动物源性变应原的前氧化活性的方法。该方法包括使非动物来源的变应原与抑制活性氧的试剂接触。筛选化合物作为减少非动物源性过敏原引发变态反应过程能力的试剂和/或作为治疗或预防变应性炎症和/或与之相关的症状的治疗剂的用途的方法是也公开了。

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