首页> 外国专利> BIODEGRADABLE/BIOACTIVE NUCLEUS PULPOSUS IMPLANT AND METHOD FOR TREATING DEGENERATED INTERVERTEBRAL DISCS

BIODEGRADABLE/BIOACTIVE NUCLEUS PULPOSUS IMPLANT AND METHOD FOR TREATING DEGENERATED INTERVERTEBRAL DISCS

机译:生物可降解/生物活性髓核植入物和治疗退化性椎间盘突出的方法

摘要

A bioactive/biodegradable nucleus implant (10) for repairing degenerated intervertebral discs that is inflated inside the nucleus space after the degenerated nucleus has been removed to re-pressurize the nuclear space within the intervertebral disc. The implant (10) is inflated with a high molecular weight fluid (14), gel or combination of fluid and elastomer, preferably an under-hydrated HA hydrogel/growth factor mixture with or without host cell. The implant (10) includes an internal, integral, self-sealing valve (16) that allows one-way filling of the implant (10) after it is placed within the disc, and is made from a material that allows fibrous in growth thereby stabilizing the implant (10). A variety of substances can be incorporated into the implant (10) to promote healing, prevent infection, or arrest pain.
机译:一种用于修复退化的椎间盘的生物活性/可生物降解的核植入物(10),该变性的椎间盘已被去除以使椎间盘内的核空间重新加压后,该植入物在核空间内膨胀。用具有或不具有宿主细胞的高分子量流体(14),凝胶或流体与弹性体的组合给植入物(10)充气,优选地是水合不足的HA水凝胶/生长因子混合物。植入物(10)包括一个内部整体式自密封阀(16),该阀可在将植入物(10)放置在椎间盘内后对其进行单向填充,并由允许纤维生长的材料制成稳定植入物(10)。可以将多种物质掺入植入物(10)中以促进愈合,防止感染或止痛。

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