MUTATED GENE CODING FOR A LAT PROTEIN AND THE BIOLOGICAL APPLICATIONS THEREOF

摘要

The present invention relates to a mutated gene coding for a mutant LAT protein leading to an exaggerated TH2 differentiation. The invention relates to biological structures containing said mutant, particularly, non-human LAT gene mutated animals, plasmids, chromosomal DNA's, embryos comprising said mutated gene, and applications thereof. The invention further relates to screening method for drug useful for treatment against asthma and allergy. Otherwise, the invention relates to method for producing IgE antibodies.